Speaker:

Dr Daniel Beard, The University of Newcastle

Project Title:

Improving Blood Flow for Better Outcomes in Stroke Patients

Project Description:

Stroke is a leading cause of disability, with current treatments reaching less than 15% of patients due to time constraints and accessibility issues. Researchers at the University of Newcastle have developed a novel therapeutic that enhances collateral blood flow to the brain during an ischaemic stroke. This innovative approach uses shear stress-activated nanoparticles to release nitroglycerin specifically in the brain’s collateral vessels, improving blood flow and preserving brain tissue. Early animal studies show promising results, suggesting this therapy could extend the treatment window and improve outcomes for stroke patients. Successful commercialization could revolutionise stroke care, increasing the number of patients eligible for reperfusion therapy and reducing disability rates.